Centenarians: Human Longevity Outliers
نویسندگان
چکیده
منابع مشابه
Genetics, lifestyle and longevity: Lessons from centenarians
Longevity as a complex life-history trait shares an ontogenetic relationship with other quantitative traits and varies among individuals, families and populations. Heritability estimates of longevity suggest that about a third of the phenotypic variation associated with the trait is attributable to genetic factors, and the rest is influenced by epigenetic and environmental factors. Individuals ...
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Centenarians are survivors, and many among them exemplify sustained competence into very old age. This paper highlights three important resilience domains among centenarians: personal resilience (e.g., personality), cognitive resilience (e.g., intellectual functioning), and social and economic resilience (e.g., social support and economic resources). Disciplines Gerontology Comments This chapte...
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In population studies of aging, the data on genetic markers are often collected for individuals from different age groups. The idea of such studies is to identify "longevity" or "frailty" genes by comparing the frequencies of genotypes in the oldest and in the younger groups of individuals. In this paper we discuss a new approach to the analysis of such data. This approach, based on the maximum...
متن کاملQuality of life and longevity: a study of centenarians.
OBJECTIVE Interest in centenarians has focused on two particular aspects: the antecedents of extreme old age and the psychophysical well-being of the very old. Our study deals with the latter aspect and aims to assess the quality of life of Italian centenarians. METHOD Using data collected using two questionnaires designed to investigate quality of life in elderly people, three groups of 38 e...
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UNLABELLED Centenarians' offspring represent a suitable model to study age-dependent variables (e.g. IGF-I) potentially involved in the modulation of the lifespan. The aim of the present study was to investigate the role of the IGF-I in human longevity. We evaluated circulating IGF-I bioactivity measured by an innovative IGF-I Kinase Receptor Activation (KIRA) Assay, total IGF-I, IGFBP-3, total...
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ژورنال
عنوان ژورنال: The Gerontologist
سال: 1997
ISSN: 0016-9013,1758-5341
DOI: 10.1093/geront/37.2.200